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AM 095 (parent compound)

AM095

CAS: 1228690-36-5

Molecular Formula: C27H24N2O5

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AM 095 (parent compound) - Names and Identifiers

Name AM095
Synonyms AM095
AM-095
AM 095
CS-1624
AM-095 FREE ACID
AM 095 FREE ACID
AM095 (free acid)
AM-095 (free base)
AM 095 (parent compound)
[4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]amino]isoxazol-5-yl]biphenyl-4-yl]acetic acid
2-[4-[4-[3-methyl-4-[[(1r)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic Acid
[1,1'-Biphenyl]-4-acetic acid, 4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]-
CAS 1228690-36-5

AM 095 (parent compound) - Physico-chemical Properties

Molecular FormulaC27H24N2O5
Molar Mass456.49
Density1.278±0.06 g/cm3(Predicted)
Boling Point641.9±55.0 °C(Predicted)
Solubility DMSO: 67.3 mg/mL
pKa4.21±0.10(Predicted)
Storage Condition-20℃
Physical and Chemical PropertiesBioactive AM095 is an antagonist of LPA1 receptor. The IC50 for human-derived recombinant LPA1 and mouse LPA1 is 0.98 μM and 0.73 μM respectively.

AM 095 (parent compound) - Upstream Downstream Industry

Raw Materials[4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]aMino]isoxazol-5-yl]biphenyl-4-yl]acetic acid ethyl ester
4-Isoxazolecarboxylic acid, 5-(4-broMophenyl)-3-Methyl-, Methyl ester
[5-(4-BroMophenyl)-3-Methylisoxazol-4-yl]carbaMic acid(R)-1-phenylethyl ester
5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid
4-(ethoxycarbonylmethyl)phenylboronic acid, pinaco
(R)-(+)-1-Phenylethanol
Ethyl 4-bromophenylacetate
Acetophenone

AM 095 (parent compound) - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.191 ml10.953 ml21.906 ml
5 mM0.438 ml2.191 ml4.381 ml
10 mM0.219 ml1.095 ml2.191 ml
5 mM0.044 ml0.219 ml0.438 ml
Last Update：2024-01-02 23:10:35

AM 095 (parent compound) - Nature

acidity coefficient (pKa) 4.21±0.10(Predicted)
Last Update：2024-04-10 22:29:15

AM 095 (parent compound) - Reference Information

biological activity AM095 is an antagonist of LPA1 receptor, and its IC50 for human recombinant LPA1 and mouse LPA1 is 0.98 μM and 0.73 μM respectively.
target TargetValue LPA1 receptor ()
TargetValue
Last Update：2024-04-09 02:00:02
AM 095 (parent compound)
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: AM095 Visit Supplier Webpage Request for quotation
CAS: 1228690-36-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: AM095freeacid Request for quotation
CAS: 1228690-36-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: AM095 (free acid) Visit Supplier Webpage Request for quotation
CAS: 1228690-36-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: AM095 Visit Supplier Webpage Request for quotation
CAS: 1228690-36-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: AM095 Visit Supplier Webpage Request for quotation
CAS: 1228690-36-5
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: AM095 (free acid) Visit Supplier Webpage Request for quotation
CAS: 1228690-36-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
AM 095 (parent compound)
Reactive Red 21
AAG
BMS-790052
116-63-2
aerfixus
Raw Materials for AM 095 (parent compound)
[4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]aMino]isoxazol-5-yl]biphenyl-4-yl]acetic acid ethyl ester
5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid
Ethyl 4-bromophenylacetate
Acetophenone
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